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NeuroPsychiatric Systemic Lupus Erythematosus (NPSLE)

“Systemic Lupus Erythematosus (SLE) is a chronic, inflammatory, multisystem disorder preponderantly affecting young women”

Clinical History:
A 27 year old female patient of Indian origin, with diagnosis of Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) was presented to Vaidyaratnam Dr. Raghavan Ramankutty in the year 2017, with Neuropsychiatric and hematological manifestation of Lupus. The patient has been diagnosed with the disease, in the year 2015.

The health of patient started deteriorating when she suddenly developed itchy rashes over both the arms in September 2014. She did not respond to prescribed antihistaminics, and the rashes disappeared, only after, short course of steroids.

Patient remained unwell for following 8 months, where she has had

  • History of frequent infections
  • A history of 2 recurrent early miscarriages
  • Frequent episodes of fever, loss of appetite, dizziness, nausea
  • Associated myalgia, Arthralgia and severe fatigue

The Investigations revealed Increased Erythrocyte Sedimentation Rate (ESR) and positive Antinuclear antibodies. She was prescribed Hydroxychloroquine, steroids and Azathioprine. There was immediate symptomatic improvement but patient developed

  • Organic psychosis after 2 months of starting the regimen
    She was hospitalized, diagnosed with Neuropsychiatric SLE (NPSLE) in the year 2015 and given Intravenous steroid therapy for 3 days followed by oral steroids and antipsychotics (olanzapine and Nitrazepam). Patient did not respond to the treatment, and she developed
  • Increased anxiety, agitation, and insomnia and binge eating disorder. She remained unresponsive to Electroconvulsive therapy which was given twice.
    Her health was deteriorating very fast and she developed new symptom of
  • Echolalia (meaningless repetition of spoken words)
    She was advised to take 2 doses of Intravenous Cyclophosphamide and other antipsychotics were modified. This stabilized her condition for some time though intermittent episodes of mood swings and anxiety were there.
    Patient was again hospitalized in the year 2016, when she had developed new symptoms of
  • Incoherent speech and flight of ideas
    Cyclophosphamide was continued for 6 months, and Antipsychotics were gradually withdrawn.

She has history of swollen lips in the year 2017, for which she was prescribed steroids.

DAT (Dathathreya Ayurveda therapy) Intervention
The treatment started after meticulous pulse examination by Dr. Raghavan Ramankutty to establish the severity of the disease, prognosis, and treatment plan. Patient was prescribed powder medicines (Herbal) and liquid medicines to improve her overall health, symptoms and to counter the side effects of steroids. She has also been prescribed a very specific oil (specially made in accordance to her constitution) to be applied on vertex daily.

Results and Conclusion
The symptoms improved within 2 months of starting Ayurveda Therapy. Her blood profile reveals the melioration in hematological parameters. There is substantial improvement in quality of life. Patient reported increased energy levels after starting Dr. Raghavan’s therapy. She is still taking the treatment. The pulse examination has revealed that her condition is stable.

Skills needed:
Ayurveda oil (CNR-SO), Ayurveda oral medications, Ayurveda powder, Ayurvedic Therapy, Ayurvedic Treatment
Lupus, Neurology And Psychiatry

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